Extrahepatic bile ducts
Dysplasia of extrahepatic bile ducts

Author: Hanni Gulwani, M.D. (see Authors page)

Revised: 8 February 2018, last major update September 2012

Copyright: (c) 2003-2018, PathologyOutlines.com, Inc.

PubMed Search: Dysplasia[TI] extrahepatic bile ducts

Cite this page: Gulwani, H. Dysplasia of extrahepatic bile ducts. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/gallbladderdysplasiaofextrahepatic.html. Accessed September 22nd, 2018.
Definition / general
  • Spectrum from hyperplasia to high grade dysplasia to invasive adenocarcinoma exists, similar to intraductal papillary mucinous neoplasms
  • High grade dysplasia at cystic duct margin is rare without invasive carcinoma (HPB (Oxford) 2011;13:865)
  • Almost universally abnormally short telomeres (Mod Pathol 2006;19:772)
Microscopic (histologic) description
  • May have prominent subnuclear vacuoles
Microscopic (histologic) images

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High grade dysplasia of cystic duct margin

Figures 3 and 4

Positive stains
Negative stains
Differential diagnosis