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Extrahepatic bile ducts



Reviewer: Hanni Gulwani, M.D. (see Reviewers page)
Revised: 15 February 2013, last major update September 2012
Copyright: (c) 2003-2013, PathologyOutlines.com, Inc.


● Incidence only 10% of carcinoma
● More common in gallbladder than extrahepatic biliary tree


● Total excision

Gross description

● 1-3 cm, usually in common bile duct
● Single or multiple
● Pedunculated or sessile

Micro description

● Tubular, tubulovillous, villous
● Low to high grade dysplasia
● Usually lined by pseudostratified columnar epithelium and composed of intestinal type glands with goblet cells, endocrine cells, Paneth cells


● Express foregut antigens (D10, 1F6, MUC6, MUC5AC, and TFF2) and secrete acid mucin (Am J Surg Pathol 2010;34:1312)

End of Extrahepatic bile ducts > Tumors > Adenoma

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