Gallbladder
Miscellaneous nontumor
Metaplasia

Author: Hanni Gulwani, M.D. (see Authors page)

Revised: 6 February 2018, last major update September 2012

Copyright: (c) 2003-2018, PathologyOutlines.com, Inc.

PubMed Search: Metaplasia[TI] gallbladder

Cite this page: Gulwani, H. Metaplasia. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/gallbladdermetaplasia.html. Accessed May 27th, 2018.
Definition / general
  • Usually gastric or intestinal, rarely squamous
  • Associated with older age, gallstones
Bone metaplasia
Case reports
Cartilaginous metaplasia
Case reports
Gastric gland metaplasia
Definition / general
  • 66 - 84% of cholecystectomy specimens
  • Pyloric, antral or mucous glands
  • Glands usually scattered in lamina propria but may extend into muscular layer
  • May form polyps
  • Don't call adenoma unless dysplasia present


Microscopic (histologic) images

Images hosted on other servers:

Various images



Positive stains
Intestinal metaplasia
Definition / general
  • Very common finding in cholecystectomy specimens (up to 86%, Sao Paulo Med J 2008;126:220)
  • Goblet cells, endocrine cells, Paneth cells, absorptive cells
  • Also pyloric gland metaplasia
  • Rarely forms polyps


Case reports

Microscopic (histologic) images

Images hosted on other servers:

Various images



Additional references
Squamous metaplasia
Case reports

Microscopic (histologic) images

Images hosted on other servers:

Various images