Extrahepatic bile ducts
Tumors
Papillomatosis


Topic Completed: 1 September 2012

Revised: 25 February 2019

Copyright: 2003-2019, PathologyOutlines.com, Inc.

PubMed Search: Papillomatosis[TI] extrahepatic bile ducts

Hanni Gulwani, M.B.B.S.
Page views in 2018: 225
Page views in 2019 to date: 191
Cite this page: Gulwani H Papillomatosis. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/gallbladderpapillomatosis.html. Accessed July 16th, 2019.
Definition / general
  • Rare; multiple and recurrent papillary adenomas in biliary tract, usually involving extrahepatic bile ducts
  • Also called adenomatosis
  • Usually ages 50 - 60 years, no gender preference
Case reports
Treatment
  • Complete excision but local recurrence is common
Gross description
  • Dilated bile ducts with thick, fibrotic walls
  • Entire mucosal surface may be replaced by papillary adenomas
  • Intraluminal mucin common
  • Adenomas are tan, soft, friable polyps without gross invasion
Microscopic (histologic) description
  • Columnar or cuboidal cells with basal nuclei overlying fibrovascular core
Microscopic (histologic) images

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