Extrahepatic bile ducts
Tumors
Papillomatosis

Author: Hanni Gulwani, M.D. (see Authors page)

Revised: 8 February 2018, last major update September 2012

Copyright: (c) 2003-2018, PathologyOutlines.com, Inc.

PubMed Search: Papillomatosis[TI] extrahepatic bile ducts

Cite this page: Gulwani, H. Papillomatosis. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/gallbladderpapillomatosis.html. Accessed July 21st, 2018.
Definition / general
  • Rare; multiple and recurrent papillary adenomas in biliary tract, usually involving extrahepatic bile ducts
  • Also called adenomatosis
  • Usually ages 50 - 60 years, no gender preference
Case reports
Treatment
  • Complete excision but local recurrence is common
Gross description
  • Dilated bile ducts with thick, fibrotic walls
  • Entire mucosal surface may be replaced by papillary adenomas
  • Intraluminal mucin common
  • Adenomas are tan, soft, friable polyps without gross invasion
Microscopic (histologic) description
  • Columnar or cuboidal cells with basal nuclei overlying fibrovascular core
Microscopic (histologic) images

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