Gallbladder
Malignant gallbladder tumors
Sarcoma


Topic Completed: 1 September 2012

Revised: 21 February 2019

Copyright: 2003-2019, PathologyOutlines.com, Inc.

PubMed Search: Sarcoma[TI] gallbladder[TI]
Page views in 2018: 161
Page views in 2019 to date: 63
Cite this page: Gulwani H Sarcoma. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/gallbladdersarcoma.html. Accessed March 23rd, 2019.
Definition / general
  • Primary gallbladder sarcoma is rare (Am J Surg Pathol 2009;33:826)
  • Malignant fibrous histiocytoma (MFH) is most common, then leiomyosarcoma, rarely angiosarcoma
  • Older female adults who usually present with acute cholecystitis, abdominal pain, weight loss, pruritus, leukocytosis, elevated alkaline phosphatase and bilirubin
  • Overall poor prognosis (Dig Dis Sci 2009;54:395), except botryoid embryonal rhabdomyosarcoma (RMS) (young children), which may have excellent prognosis
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