Cite this page: Gulwani, H. Sarcoma. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/gallbladdersarcoma.html. Accessed August 18th, 2018.
Definition / general
- Primary gallbladder sarcoma is rare (Am J Surg Pathol 2009;33:826)
- Malignant fibrous histiocytoma (MFH) is most common, then leiomyosarcoma, rarely angiosarcoma
- Older female adults who usually present with acute cholecystitis, abdominal pain, weight loss, pruritus, leukocytosis, elevated alkaline phosphatase and bilirubin
- Overall poor prognosis (Dig Dis Sci 2009;54:395), except botryoid embryonal rhabdomyosarcoma (RMS) (young children), which may have excellent prognosis