Malignant gallbladder tumors

Topic Completed: 1 September 2012

Revised: 12 September 2019

Copyright: 2003-2019,, Inc.

PubMed Search: Sarcoma[TI] gallbladder[TI]

Hanni Gulwani, M.B.B.S.
Page views in 2018: 161
Page views in 2019 to date: 203
Cite this page: Gulwani H. Sarcoma. website. Accessed November 13th, 2019.
Definition / general
  • Primary gallbladder sarcoma is rare (Am J Surg Pathol 2009;33:826)
  • Malignant fibrous histiocytoma (MFH) is most common, then leiomyosarcoma, rarely angiosarcoma
  • Older female adults who usually present with acute cholecystitis, abdominal pain, weight loss, pruritus, leukocytosis, elevated alkaline phosphatase and bilirubin
  • Overall poor prognosis (Dig Dis Sci 2009;54:395), except botryoid embryonal rhabdomyosarcoma (RMS) (young children), which may have excellent prognosis
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