Gallbladder
Malignant gallbladder tumors
Sarcoma

Author: Hanni Gulwani, M.D. (see Authors page)

Revised: 7 February 2018, last major update September 2012

Copyright: (c) 2003-2018, PathologyOutlines.com, Inc.

PubMed Search: Sarcoma[TI] gallbladder[TI]

Cite this page: Gulwani, H. Sarcoma. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/gallbladdersarcoma.html. Accessed November 17th, 2018.
Definition / general
  • Primary gallbladder sarcoma is rare (Am J Surg Pathol 2009;33:826)
  • Malignant fibrous histiocytoma (MFH) is most common, then leiomyosarcoma, rarely angiosarcoma
  • Older female adults who usually present with acute cholecystitis, abdominal pain, weight loss, pruritus, leukocytosis, elevated alkaline phosphatase and bilirubin
  • Overall poor prognosis (Dig Dis Sci 2009;54:395), except botryoid embryonal rhabdomyosarcoma (RMS) (young children), which may have excellent prognosis