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TNM staging for Carcinoma of gallbladder and cystic duct

Reviewer: Hanni Gulwani, M.D. (see Reviewers page)
Revised: 10 February 2013, last major update September 2012
Copyright: (c) 2003-2013, PathologyOutlines.com, Inc.


● Classification excludes sarcomas and carcinoid tumors

Primary tumor (T) - carcinoma of gallbladder and cystic duct

TX: Primary tumor cannot be assessed
T0: No evidence of primary tumor
Tis: Carcinoma in situ
T1: Tumor invades lamina propria or muscular layer
T1a: Tumor invades lamina propria
T1b: Tumor invades muscular layer
T2: Tumor invades perimuscular connective tissue; no extension beyond serosa or into liver
T3: Tumor perforates the serosa (visceral peritoneum) or directly invades the liver or one other adjacent organ or structure, such as the stomach, duodenum, colon, pancreas, omentum or extrahepatic bile ducts
T4: Tumor invades main portal vein or hepatic artery or invades two or more extrahepatic organs or structures

Regional lymph nodes (N) - carcinoma of gallbladder and cystic duct

NX: Regional lymph nodes cannot be assessed
N0: No regional lymph node metastasis
N1: Metastasis to nodes along the cystic duct, common bile duct, hepatic artery or portal vein
N2: Metastases to periaortic, pericaval, superior mesenteric artery or celiac artery lymph nodes

Distant metastasis (M) - carcinoma of gallbladder and cystic duct

M0: No distant metastasis
M1: Distant metastasis

Stage grouping- carcinoma of gallbladder and cystic duct

0: Tis N0 M0
I: T1 N0 M0
II: T2 N0 M0
IIIA: T3 N0 M0
IIIB: T1-3 N1 M0
IVA: T4 N0-1 M0
IVB: any T N2 M0 or any T any N M1


Pathologic Staging (pTNM)

TNM Descriptors (required only if applicable) (select all that apply)
___ m (multiple primary tumors)
___ r (recurrent)
___ y (posttreatment)

End of Gallbladder > Miscellaneous > TNM staging for Carcinoma of gallbladder and cystic duct

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