Cardiac tumors - malignant
Malignant peripheral nerve sheath tumor

Topic Completed: 1 November 2013

Revised: 27 September 2019

Copyright: 2007-2019, PathologyOutlines.com, Inc.

PubMed Search: Malignant peripheral nerve sheath tumor [title] heart

Nat Pernick, M.D.
Page views in 2018: 97
Page views in 2019 to date: 74
Cite this page: Pernick N. Malignant peripheral nerve sheath tumor. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/hearttumorMPNST.html. Accessed October 16th, 2019.
Definition / general
  • Tapered spindle cells of neurogenic origin by morphology, ultrastructure or immunohistochemistry
  • Also called malignant schwannoma
  • Very rare
Case reports
Microscopic (histologic) images
Missing Image

Spindle cell tumor
with sweeping, plexiform
growth pattern and
a neural appearance
Missing Image

Large epicardial nodule,
focally S100+, with
spindle cells showing
irregular nuclear contours
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