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General
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Case reports
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Treatment
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Gross description
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Gross images
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Various images

Micro description
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Micro images
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Right atrial mass in 20 year old woman

Atypical papillary fronds lined by hyperchromatic endothelial cells

Cellular area with plump, atypical endothelial cells and mitotic activity, but no obvious vascular channels

Spindle cell tumor with poorly formed vascular structures and extravasated red blood cells


Neovascular channels contain RBCs within a fibrous stroma

Fig 1: transesophageal echocardiography shows large
echo-dense mass involving interatrial septum and protruding
into right atrium; fig 2: anastomosing vascular channels
composed of pleomorphic/hyperchromatic spindle cells

Metastasis to lung

CD31+

Factor VIII related antigen+ within cytoplasm

Cytology description
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Positive stains
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Negative stains
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Electron microscopy description
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Electron microscopy images
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Abundant cytoplasm with membrane bound vesicles and rough ER

Focal endothelial differentiation

Differential diagnosis
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Additional references
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End of Heart tumor > Cardiac tumors - malignant > Angiosarcoma



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