Pathology Outlines

Heart
Cardiac tumors - malignant
Lymphoma

Author: Nat Pernick, M.D.

Topic Completed: 1 November 2013

Revised: 4 March 2019

Copyright: 2007-2019, PathologyOutlines.com, Inc.

PubMed Search: Lymphoma [title] heart review[ptyp]

Page views in 2018: 157

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Table of Contents

Cite this page: Pernick N Lymphoma. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/hearttumorlymphoma.html. Accessed June 19th, 2019.

Definition / general

Rare; associated with HIV or other immunocompromise
Primary if all of tumor is within pericardium; otherwise secondary
Primary tumors are rare
Most common subtype is diffuse large B cell lymphoma (Arch Mal Coeur Vaiss 2005;98:875, Leuk Lymphoma 2004;45:781)
Poor prognosis, since usually advanced disease
Not associated with EBV (Arch Pathol Lab Med 1996;120:555)

Case reports

29 year old man with anaplastic large cell lymphoma presenting with embolic stroke (Blood 2003;101:4708)
Elderly man with Burkitt lymphoma mimicking acute pulmonary embolism (J Coll Physicians Surg Pak 2006;16:536)
Female patient with primary cardiac lymphoma and complete atrioventricular block (Acta Cardiol 2007;62:55)
Adult T cell leukemia / lymphoma with massive cardiac involvement (Arch Pathol Lab Med 1991;115:1052)
Diffuse large B cell lymphoma with hemophagocytic syndrome (Haematologica 2002;87:ECR27)

Gross description