Cardiac tumors - malignant
Malignant mesenchymoma

Topic Completed: 1 November 2013

Revised: 27 September 2019

Copyright: 2007-2019, PathologyOutlines.com, Inc.

PubMed Search: Malignant mesenchymoma heart

Nat Pernick, M.D.
Page views in 2018: 163
Page views in 2019 to date: 198
Cite this page: Pernick N. Malignant mesenchymoma. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/hearttumormalignantmesenchymoma.html. Accessed October 16th, 2019.
Definition / general
  • Sarcomatous tumor with two or more distinct types of cellular differentiation other than fibrosarcoma
  • AFIP Third Fascicle (soft tissue) and WHO (soft tissue) dislike this terminology, and recommend (a) describing as mixed mesenchymal neoplasm and specifying the components or (b) classifying based on predominant mode of differentiation and mentioning the other component(s)
  • Rare
  • Mean age 42 years, 2/3 female
  • Usually left atrium or mitral valve
  • Mean survival is 20 months
Case reports
Microscopic (histologic) description
  • Common components are osteosarcoma, chondrosarcoma, rhabdomyosarcoma, angiosarcoma and liposarcoma
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