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General
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Case reports
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Treatment
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Gross description
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Gross images
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Rhabdomyomatosis in patient with tuberous sclerosis and multiple minute tumors studding epicardium

Right ventricular mass

Left ventricular tumor causing sudden death in children ages 1-2

Micro description
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Micro images
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Spider cell (center) and intracellular myofilaments (oil emersion)

Drawings from 1938 report

Muscle specific actin highlights spider cells and cross striations (arrowheads)


Fig A: well circumscribed, tan-yellow masses in left atrium and left ventricle
Fig B: large cells with clear cytoplasm (spider cells)
Fig C: spider cells surrounded by normal myocytes

Positive stains
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Negative stains
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Electron microscopy description
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Electron microscopy description
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Abundant glycogen, small and sparse mitochondria, fragmented irregular myofilaments with Z bands

Differential diagnosis
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Additional references
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End of Heart tumor > Cardiac tumors - benign > Rhabdomyoma



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