Heart
Malignant tumors
Embryonal Rhabdomyosarcoma of heart


Topic Completed: 1 December 2013

Minor changes: 27 September 2019

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PubMed Search: Embryonal Rhabdomyosarcoma of heart

Related Topics: Rhabdomyosarcoma, Alveolar Rhabdomyosarcoma

Nat Pernick, M.D.
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Cite this page: Pernick N. Embryonal Rhabdomyosarcoma of heart. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/hearttumorrmsembryonal.html. Accessed July 7th, 2020.
Definition / general
  • Usually infants, children and young adults
Case reports
Gross description
  • Grape-like structures (sarcoma botyroides variant)
Gross images

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Left atrial tumor with hemorrhage and necrosis

Microscopic (histologic) description
  • Small cell tumor with rhabdomyoblasts
  • Cambium layer may be present
  • Variable tadpole shaped rhabdomyoblasts
  • Some cells have cross striations on high power
Microscopic (histologic) images

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Spindle cells with abundant cytoplasm (left atrial mass)

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Cross striations in some tumor cells

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Rhabdomyoblasts are scattered
cells with abundant cytoplasm
in an otherwise undifferentiated
embryonal sarcoma


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Cross striations in some tumor cells

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Desmin+

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Tadpole shaped rhabdomyoblasts
and large cells with abundant
eosinophilic cytoplasm and
pleomorphic nuclei
Electron microscopy images

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Band of filaments

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