Nonneoplastic disease
Carpal tunnel syndrome

Author: Vijay Shankar, M.D. (see Authors page)

Revised: 11 August 2017, last major update December 2012

Copyright: (c) 2002-2017,, Inc.

PubMed search: Joints carpal tunnel syndrome [title]

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Cite this page: Shankar, V. Carpal tunnel syndrome. website. Accessed February 21st, 2019.
Definition / general
  • Carpal tunnel: space between flexor retinaculum (transverse carpal ligament) and carpal bones, through which median nerve travels
  • Syndrome is an entrapment neuropathy
  • Symptoms due to compression of median nerve by trauma, masses within canal (hemangioma, lipoma, ganglia), rheumatoid arthritis, amyloidosis
Clinical features
  • Pain, often accompanied by parasthesia in distribution of median nerve
  • Rarely wasting of thenar muscles
Case reports
  • Surgical; division of transverse carpal ligament
Clinical images

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Lesion with incision marking

Giant lipoma stretching median nerve

2 years follow up

Gross description
  • Nerve appears constricted and pale
Gross images

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Resected giant lipoma

Microscopic (histologic) description
  • Transverse carpal ligament shows nonspecific fibrosis