Nonneoplastic disease
Carpal tunnel syndrome

Topic Completed: 1 December 2012

Minor changes: 26 September 2019

Copyright: 2002-2019,, Inc.

PubMed search: Joints carpal tunnel syndrome [title]

Vijay Shankar, M.D.
Page views in 2019: 922
Page views in 2020 to date: 338
Cite this page: Shankar V. Carpal tunnel syndrome. website. Accessed May 24th, 2020.
Definition / general
  • Carpal tunnel: space between flexor retinaculum (transverse carpal ligament) and carpal bones, through which median nerve travels
  • Syndrome is an entrapment neuropathy
  • Symptoms due to compression of median nerve by trauma, masses within canal (hemangioma, lipoma, ganglia), rheumatoid arthritis, amyloidosis
Clinical features
  • Pain, often accompanied by parasthesia in distribution of median nerve
  • Rarely wasting of thenar muscles
Case reports
  • Surgical; division of transverse carpal ligament
Clinical images

Images hosted on other servers:


Lesion with incision marking

Giant lipoma stretching median nerve

2 years follow up

Gross description
  • Nerve appears constricted and pale
Gross images

Images hosted on other servers:

Resected giant lipoma

Microscopic (histologic) description
  • Transverse carpal ligament shows nonspecific fibrosis
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