Noninfective arthritis
Enteropathic arthritis

Author: Vijay Shankar, M.D. (see Authors page)

Revised: 29 August 2017, last major update April 2013

Copyright: (c) 2002-2017,, Inc.

PubMed Search: Enteropathic arthritis [title]

Cite this page: Shankar, V. Enteropathic arthritis. website. Accessed August 19th, 2018.
Definition / general
  • Subset of spondyloarthritides and seronegative arthritis
  • Lipopolysaccharide antigens stimulate immune system and cause abrupt onset of arthritis in knees and ankles, lasts only 1 year
  • Can be associated with inflammatory bowel disease, Crohn's disease and ulcerative colitis (J Postgrad Med 2005;51:273, World J Gastroenterol 2009;15:2456)
  • Also associated with celiac disease, Whipple disease, collagenous colitis, intestinal bypass surgery
  • More common in males with peak incidence at 15 - 35 years
  • Due to bowel infection with Yersinia, Salmonella, Shigella, Campylobacter
Clinical features
  • Usually asymmetric, oligoarticular arthritis involving the lower limbs along with gastrointestinal manifestations of IBD
Prognostic factors
  • IBD related arthritis usually carries worse prognosis
Case reports
  • 58 year old Malay woman with 17 year history of ulcerative colitis with persistent knee effusion (J Med Case Rep 2012;6:10)
Microscopic (histologic) images

Images hosted on other servers:

Synovial tissue of knee