Table of ContentsDefinition / general | Case reports | Treatment | Gross images | Microscopic (histologic) description | Microscopic (histologic) images
Cite this page: Sangle N. Actinomycosis. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/kidneyactinomycosis.html. Accessed January 27th, 2020.
Definition / general
- Actinomyces are anaerobic, gram positive, non acid fast filamentous bacteria that are normal flora in mouth, vagina, GI tract
- Cause chronic suppurative and granulomatous disease of cervicofacial, thoracic or abdominal region
- Sometimes called the most "misdiagnosed disease" because abscesses can mimic malignancy and may lead to unnecessary surgical resections (South Med J 2004;97:316, Am J Surg Pathol 2000;66:85)
- Actinomyces israelii: usual cause of Actinomyces abscesses; also most common cause of disseminated actinomycosis, secondary to GI perforation (diverticulitis, appendicitis) or procedures, IUD, aspiration, poor oral hygiene / dental procedures
- 11 year old girl with 4 cm kidney tumor and multiple 1 - 2 mm lung nodules (Case of the Week #244)
- 39 year old man with sinus tracts (Radiology 2007;244:309)
- 46 year old woman with retroperitoneal mass (Infect Dis Obstet Gynecol 2011;2011:747059)
- 50 year old woman with solitary renal cyst (Indian J Urol 2008;24:416)
- 53 year old man with poor oral hygiene (Urol J 2010;7:80)
- 74 year old with coexisting renal vein thrombosis (Clin Nephrol 2012;77:156)
- Antibiotics; possibly nephrectomy
Microscopic (histologic) description
- Marked acute and chronic inflammation with occasional "sulfur granules"