Kidney nontumor
Glomerular disease
Other primary glomerular disease
Chronic glomerulonephritis

Topic Completed: 3 September 2012

Minor changes: 12 February 2020

Copyright: 2002-2020,, Inc.

PubMed Search: Chronic glomerulonephritis [title] "loattrfree full text"[sb]

Nikhil Sangle, M.D.
Page views in 2019: 7,142
Page views in 2020 to date: 4,514
Cite this page: Sangle N. Chronic glomerulonephritis. website. Accessed September 23rd, 2020.
Definition / general
  • An end stage disease, due to progression of various types of glomerulonephritis; occasionally no prior history of kidney disease (eMedicine: Chronic Glomerulonephritis [Accessed 12 February 2020])
  • Rates of progression: rapidly progressive (90%), post streptococcal (1% children, 5% adults), focal and segmental glomerulosclerosis (50 - 80%, rapid), membranous (50%), membranoproliferative (50%), IgA nephropathy (30 - 50%, slow)
  • Paradoxically, nephrotic syndrome symptoms decrease as glomeruli disappear
Gross description
  • Symmetrically small kidneys with thin granular cortex and increased peripelvic fat
Gross images

Images hosted on other servers:

Bilaterally small kidneys

Microscopic (histologic) description
  • Glomerulosclerosis, tubular atrophy and thyroidization, interstitial fibrosis and lymphocytic inflammation
  • Arterial and arteriolar sclerosis
Microscopic (histologic) images

Images hosted on other servers:

End stage kidney with sclerotic glomeruli, tubular thyroidization, interstitial fibrosis and thickened arterial walls

Various images


Chronic glomerulonephritis

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