Kidney non-tumor - Dioctophyma renale

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Kidney non-tumor

Infections / parasites

Dioctophyma renale

Reviewers: Nikhil Sangle, M.D. (see Reviewers page)
Revised: 1 September 2012, last major update September 2012
Copyright: (c) 2003-2012, PathologyOutlines.com, Inc.

General
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● Also called giant kidney worm
● Found in dogs, minks, cats, other fish-eating mammals
● Adult worms live in renal pelvis, their eggs incite a granulomatous response
● Adult worms progressively destroy renal parenchyma until only kidney and worm remain

Case reports
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● 47 year old farmer in Australia (Am J Surg Pathol 1983;7:281)
● 50 year old Chinese man with cyst in upper kidney (Am J Surg Pathol 1986;10:508)
● 51 year old woman with fatal bilateral dioctophymatosis (J Parasitol 2010;96:1152)

Gross description
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● Hemorrhagic cyst, often thick walled

Gross images
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Kidney and worms

Micro description
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● Cyst wall composed of granulomatous tissue with eggs and cross striations of parasites
● Eggs have birefringent striated double wall

Micro images
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Left: various images; right: eggs (arrows) and granulomatous response

Differential diagnosis
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● Liesegang rings (Diagn Cytopathol 1990;6:197)

End of Kidney non-tumor > Infections / parasites > Dioctophyma renale

Ref Updated: 6/26/12

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