Cite this page: Sangle N. Focal proliferative and necrotizing glomerulonephritis. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/kidneyfocalprolif.html. Accessed September 22nd, 2019.
Definition / general
- Only parts of some glomeruli affected; proliferative, not sclerotic; also necrosis and fibrin deposition
- Hematuria varies from microscopic to gross, occasionally with nephrotic syndrome
- Seen early in systemic diseases (SLE, Henoch-Schönlein purpura, Goodpasture syndrome, endocarditis, granulomatosis with polyangiitis (Wegener's))
- May be part of IgA nephropathy or idiopathic