Kidney non-tumor - Microsporidiosis

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Kidney non-tumor

Infections / parasites

Microsporidiosis

Reviewer: Nikhil Sangle, M.D. (see Reviewers page)
Revised: 1 September 2012, last major update September 2012
Copyright: (c) 2003-2012, PathologyOutlines.com, Inc.

General
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● Emerging pathogens causing life-threatening infections in organ transplant recipients
● Can cause peristent diarrhea (J Clin Microbiol 2011;49:1301) or fever of unknown origin (Transpl Infect Dis 2009;11:83)

Case reports
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● 45 year old woman with living related donor transplant on high-dose steroids for acute rejection (Arch Pathol Lab Med 2003;127:e224)

Micro images
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Interstitial inflammation and tubular damage

Spores in urine sample

Figure 1: Intra- and extracellular small spherical structures with dense neutrophilic infiltrates
Figure 2: EM shows spherical organisms with vacuoles and membrane bound granular material
Figure 3: spores from conjunctival scrapings
Figure 4: punctate areas of necrosis in brain at autopsy

End of Kidney non-tumor > Infections / parasites > Microsporidiosis

Ref Updated: 6/29/12

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