Kidney nontumor
Renal hormones

Author: Nikhil Sangle, M.D. (see Authors page)

Revised: 11 September 2017, last major update April 2012

Copyright: (c) 2002-2017,, Inc.

PubMed Search: Renal hormones [title]

Cite this page: Sangle, N. Renal hormones. website. Accessed October 23rd, 2018.
Definition / general
  • Aldosterone:
    • Causes increased reabsorption of NaCl to increase blood volume
  • Antidiuretic hormone (vasopressin):
    • Stimulates water reabsorption by stimulating insertion of "water channels" or aquaporins (Google: Aquaporins - Water Channels) into the membranes of kidney tubules
    • These channels transport solute free water through tubular cells and back into blood, leading to a decrease in plasma osmolarity and an increased osmolarity of urine
    • In diabetes insipidus (without ADH), kidney tubules are virtually impermeable to water, which flows out as urine (up to 10 liters of dilute urine/day)
  • Erythropoietin:
    • Secreted in response to low serum pO2, promotes red blood cell production
  • Natriuretic hormones:
    • Cause increase in glomerular filtration rate after nephron destruction
  • Renin:
    • Produced by juxtaglomerular apparatus in response to hypotension, converts angiotensinogen to angiotensin I, which is converted to angiotensin II in the lung by angiotensin converting enzyme (ACE)
    • Angiotensin II increases aldosterone production and promotes vasoconstriction
Diagrams / tables

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Renin pathway