Kidney nontumor
General
Renal hormones


Topic Completed: 2 April 2012

Revised: 1 October 2019

Copyright: 2002-2019, PathologyOutlines.com, Inc.

PubMed Search: Renal hormones [title]

Nikhil Sangle, M.D.
Page views in 2019: 616
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Cite this page: Sangle N. Renal hormones. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/kidneyrenalhormones.html. Accessed January 18th, 2020.
Definition / general
  • Aldosterone:
    • Causes increased reabsorption of NaCl to increase blood volume
  • Antidiuretic hormone (vasopressin):
    • Stimulates water reabsorption by stimulating insertion of "water channels" or aquaporins (Google: Aquaporins - Water Channels) into the membranes of kidney tubules
    • These channels transport solute free water through tubular cells and back into blood, leading to a decrease in plasma osmolarity and an increased osmolarity of urine
    • In diabetes insipidus (without ADH), kidney tubules are virtually impermeable to water, which flows out as urine (up to 10 liters of dilute urine/day)
  • Erythropoietin:
    • Secreted in response to low serum pO2, promotes red blood cell production
  • Natriuretic hormones:
    • Cause increase in glomerular filtration rate after nephron destruction
  • Renin:
    • Produced by juxtaglomerular apparatus in response to hypotension, converts angiotensinogen to angiotensin I, which is converted to angiotensin II in the lung by angiotensin converting enzyme (ACE)
    • Angiotensin II increases aldosterone production and promotes vasoconstriction
Diagrams / tables

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Renin pathway

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