Kidney nontumor / medical renal

Infection

Tuberculosis



Last author update: 7 January 2013
Last staff update: 20 July 2022

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PubMed Search: Tuberculosis kidney pathology

Nikhil Sangle, M.D.
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Cite this page: Sangle N. Tuberculosis. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/kidneytb.html. Accessed March 28th, 2024.
Definition / general
Clinical features
  • Renal involvement may be indolent, may not become apparent until 20+ years from detection of primary infection
  • Urogenital TB is associated with unilateral nonfunctioning kidney in 27% of cases, with renal failure present in 7% (Int J Urol 2008;15:827)
  • In chronic kidney disease of all causes, one study from India demonstrated a 4% incidence of TB, which was usually tuberculin skin test negative (Clin Nephrol 2007;67:217)
  • In immunocompromised patients, urogenital TB usually has systemic symptoms, dissemination, multiple renal foci (Int Urol Nephrol 2009;41:327)
Case reports
Radiology images

Images hosted on other servers:

Renal tuberculosis

Gross description
  • Multiple cavities filled with yellow friable necrotic material
Gross images

Case #128

Renal tuberculosis



Images hosted on other servers:

Renal tuberculosis

Microscopic (histologic) description
  • Extensive caseous necrosis, with occasional granulomas composed of epithelioid cells and Langhans giant cells with surrounding lymphocytes
  • Very early granulomas might not show caseation
  • The interface of viable cells and caseous necrosis is where acid fast bacilli (AFB) are most found
Microscopic (histologic) images

Case #128

Various images



Images hosted on other servers:

Various images

Miliary tuberculosis - kidney

Differential diagnosis
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