Kidney tumor - adult malignancies
Benign (usually) adult tumors
2004 WHO classification of renal tumors

Author: Pallav Gupta, M.D. (see Authors page)

Revised: 6 January 2016, last major update January 2016

Copyright: (c) 2003-2016, PathologyOutlines.com, Inc.

PubMed Search: 2004 WHO classification [title] renal tumors
Definition / General
Classification

Kidney tumors in infants and children (WHO):

  • Nephroblastic tumors:
    • Nephroblastoma
      • Favorable histology
      • Unfavorable histology (diffuse / focal anaplasia)
    • Nephrogenic rests and nephroblastomatosis
    • Cystic nephroma and cystic partially differentiated nephroblastoma
    • Metanephric tumors
      • Metanephric adenoma
      • Metanephric adenofibroma
      • Metanephric stromal tumor
  • Mesoblastic nephroma:
    • Classic
    • Cellular
    • Mixed
  • Clear cell carcinoma
  • Rhabdoid tumor of kidney
  • Renal epithelial tumors of childhood:
    • Papillary renal cell carcinoma
    • Renal medullary carcinoma
    • Translocation associated RCC (Xp11.2 / t(6;11) translocations)
  • Rare tumors:
    • Ossifying renal tumor of infancy
    • Angiomyolipoma

Renal tumors and tumor-like conditions of adults (WHO):

  • Renal cell tumors:
    • Clear cell renal cell carcinoma
    • Multilobular clear cell renal cell carcinoma
    • Papillary renal cell carcinoma
    • Chromophobe renal cell carcinoma
    • Carcinoma of the collecting ducts of Bellini
    • Renal medullary carcinoma
    • Xp11 translocation carcinoma
    • Carcinoma associated with neuroblastoma
    • Mucinous tubular and spindle cell carcinoma
    • Renal cell carcinoma, unclassified
    • Papillary adenoma
    • Oncocytoma
  • Metanephric tumors:
    • Metanephric adenoma
    • Metanephric adenofibroma
    • Metanephric stromal tumor
  • Neuroendocrine tumors:
    • Carcinoid
    • Neuroendocrine carcinoma
    • Primitive neuroendocrine tumor (PNET)
    • Neuroblastoma
    • Pheochromocytoma
  • Mesenchymal tumors:
    • Angiomyolipoma
    • Epithelioid angiomyolipoma
    • Medullary fibroma
    • Leiomyoma
    • Lipoma
    • Hemangioma
    • Lymphangioma
    • Other benign mesenchymal tumors
    • Leiomyosarcoma
    • Liposarcoma
    • Solitary fibrous tumor
    • Hemangiopericytoma
    • Fibrosarcoma and malignant fibrous histiocytoma
    • Rhabdomyosarcoma
    • Angiosarcoma
    • Osteosarcoma
    • Synovial sarcoma
    • Other malignant mesenchymal tumors
  • Mixed mesenchymal and epithelial tumors:
    • Cystic nephroma
    • Mixed epithelial and stromal tumor
    • Synovial sarcoma
  • Germ Cell Tumors
    • Teratoma
    • Choriocarcinoma
  • Hematopoietic and Lymphoid tumors:
    • Lymphoma
    • Leukemia
    • Plasmacytoma
  • Metastatic tumors:
    • Metastatic tumors
  • Rare tumors:
    • Juxtaglomerular cell tumor
    • Nephroblastoma and other "pediatric" renal tumors
  • Tumor-like lesions:
    • Xanthogranulomatous pyelonephritis
    • Inflammatory myofibroblastic pseudotumor
Additional References