Kidney tumor - cysts, children, adult benign - Fibroepithelioid polyp of renal pelvis

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Kidney tumor - cysts, children, adult benign

Benign (usually) adult tumors

Fibroepithelioid polyp of renal pelvis

Reviewers: Mandolin Ziadie, M.D. (see Reviewers page)
Revised: 27 January 2012, last major update January 2012
Copyright: (c) 2003-2012, PathologyOutlines.com, Inc.

General
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● Mesodermal tumor that is more commonly diagnosed in the ureter

Epidemiology
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● Rare (< 50 cases reported)

Clinical features
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● Presents in young adults (usually women) with gross and painless hematuria
● X-ray: polypoid filling defect on intravenous pyelogram

Radiological images
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Polypoid filling defect on intravenous pyelogram

Case Reports
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● 57 year old woman with abdominal pain and microscopic hematuria (Arch Pathol Lab Med 1999;123:850)

Treatment
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● Benign; local resection if causes obstruction

Gross description
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● Polypoid exophytic mass with smooth glistening external surface and gray-white-pink cut surface

Gross images
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Large polyp almost completely fills renal pelvis

Micro description
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● Thick fibrous stalk and connective tissue core covered by urothelium
● Connective tissue core contains collagen, smooth muscle and blood vessels with edema and inflammatory cells

Micro images
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Urothelium covers fibrovascular tissue with loose stroma and small blood vessels

Negative stains
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● CD34

Differential diagnosis
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● Hemangioma: vascular lesion, no fibrous stalks and no urothelial cells
● Leiomyoma: smooth muscle cells, no fibrovascular stalks and no urothelium
● Schwannoma: neural features, no smooth muscle cells, no fibrovascular stalks and no urothelium; S100+

End of Kidney tumor - cysts, children, adult benign > Benign (usually) adult tumors > Fibroepithelial polyp of renal pelvis

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