Kidney tumor - cysts, children, adult benign

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Kidney tumor - cysts, children, adult benign

Benign (usually) adult tumors

Leiomyoma

Reviewers: Mandolin Ziadie, M.D. (see Reviewers page)
Revised: 27 March 2012, last major update January 2012
Copyright: (c) 2003-2012, PathologyOutlines.com, Inc.

General
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● Benign tumor of smooth muscle usually located in the cortex or, rarely in the renal capsule (Acta Radiol 2006;47:752)

Clinical features
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● Usually an incidental finding
● Most occur in adults; tumors of significant size are more common in young women

Case reports
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● 57 year old woman (Histol Histopathol 2007;22:883)

Gross images
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Firm circumscribed tumor with a whorled cut surface

28 cm tumor

Micro description
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● Well-circumscribed lesion of benign smooth muscle cells
● Features suggestive of leiomyosarcoma include mitoses, nuclear pleomorphism, necrosis

Micro images
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Leiomyoma

Positive stains
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● Alpha smooth muscle actin, h-caldesmon, calponin, muscle actin, myosin and desmin

Differential diagnosis
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● Angiomyolipoma: usually vascular and lipomatous components; positive for melanocytic markers

End of Kidney tumor - cysts, children, adult benign > Benign (usually) adult tumors > Leiomyoma

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