Kidney tumor - adult malignancies
Adult renal cell carcinoma
Lymphoepithelioma-like carcinoma

Author: Sean Williamson, M.D. (see Authors page)

Revised: 1 February 2017, last major update June 2012

Copyright: (c) 2003-2017,, Inc.

PubMed Search: Lymphoepithelioma-like carcinoma kidney

Cite this page: Lymphoepithelioma-like carcinoma. website. Accessed January 19th, 2018.
Definition / general
  • Undifferentiated carcinoma with prominent lymphoid stroma
  • Rare in kidney
  • May be considered a variant of urothelial carcinoma in renal pelvis (Mod Pathol 2006;19:494)
Case reports
Microscopic (histologic) description
  • Undifferentiated round or spindle cell carcinoma will ill defined borders, arranged in syncytial sheets or small clusters of cells, with abundant inflammatory cells including: T cells, plasma cells, eosinophils, macrophages; indistinguishable microscopically from nasopharyngeal undifferentiated carcinoma (or lymphoepithelioma)
Microscopic (histologic) images

Images hosted on other servers:

Sheets and nests of high grade tumor cells in a syncytial pattern with prominent lymphocytes

Syncytial arrangement of
tumor cells surrounded
by lymphocytes

Positive stains
Negative stains
Differential diagnosis