Kidney tumor - adult malignancies
Adult renal cell carcinoma
Lymphoepithelioma-like carcinoma

Author: Sean Williamson, M.D. (see Authors page)

Revised: 1 February 2017, last major update June 2012

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PubMed Search: Lymphoepithelioma-like carcinoma kidney

Cite this page: Lymphoepithelioma-like carcinoma. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/kidneytumormalignantLEL.html. Accessed April 24th, 2017.
Definition / General
  • Undifferentiated carcinoma with prominent lymphoid stroma
  • Rare in kidney
  • May be considered a variant of urothelial carcinoma in renal pelvis (Mod Pathol 2006;19:494)
Case Reports
Micro Description
  • Undifferentiated round or spindle cell carcinoma will ill defined borders, arranged in syncytial sheets or small clusters of cells, with abundant inflammatory cells including: T cells, plasma cells, eosinophils, macrophages; indistinguishable microscopically from nasopharyngeal undifferentiated carcinoma (or lymphoepithelioma)
Micro Images

Images hosted on other servers:

Sheets and nests of high grade tumor cells in a syncytial pattern with prominent lymphocytes

Syncytial arrangement of
tumor cells surrounded
by lymphocytes

Positive Stains
Negative Stains
Differential Diagnosis