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Kidney tumor

Adult malignancies - Miscellaneous

Frozen sections / intraoperative consultations

Reviewers: Sean Williamson, M.D. (see Reviewers page)
Revised: 13 July 2012, last major update July 2012
Copyright: (c) 2003-2012, PathologyOutlines.com, Inc.


● Assessment of surgical margins often performed in partial nephrectomy cases (Urology 2006;67:923, Scand J Urol Nephrol 2005;39:222)
● However, clinical significance may be limited, as only rare patients harbor residual disease in a follow-up radical nephrectomy specimen or repeated partial resection of margin
● Recurrence due to positive margin is uncommon (Urology 2011;77:1400, J Urol 2005;173:385)

Other indications:
● Solid renal mass in unusual setting, synchronous renal and extrarenal masses, cystic renal lesions, multiple renal masses, solid mass in diffusely cystic kidney (Arch Pathol Lab Med 2005;129:1585)
● However, no consensus exists (J Urol 2008;179:461)
● Cystic and spindle cell tumors are often misdiagnosed
● Clear cell renal cell carcinoma can be confused with inflammatory lesions, particularly those that contain foamy histiocytes

Gross images

Renal cystic tumors

Micro images (frozen sections)

Clear cell renal cell carcinoma, xanthogranulomatous pyelonephritis and malakoplakia

Urothelial, collecting duct and papillary carcinomas

Oncocytoma versus chromophobe carcinoma


Renal cystic tumors

End of Kidney tumor > Adult malignancies - Miscellaneous > Frozen sections / intraoperative consultations

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