Kidney tumor
Other adult malignancies
Hemangiopericytoma

Author: Sean R. Williamson, M.D.

Revised: 19 April 2018, last major update June 2012

Copyright: (c) 2003-2018, PathologyOutlines.com, Inc.

PubMed Search: Hemangiopericytoma kidney

Cite this page: Williamson, S.R. Hemangiopericytoma. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/kidneytumormalignanthpc.html. Accessed September 26th, 2018.
Definition / general
  • Rare; < 50 cases reported
  • May arise in perirenal tissues or renal capsule with secondary invasion of kidney
Epidemiology
  • Often older patients; may be associated with hypoglycemia
Case reports
Gross description
  • Large circumscribed tumor
Gross images

Images hosted on other servers:

Well circumscribed tumor

Microscopic (histologic) description
  • Rich network of branching vessels with staghorn configuration, lined by single layer of endothelium, surrounded by haphazard pattern of round / oval tumor cells with indistinct cell borders
Microscopic (histologic) images

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H&E and silver stain

Thin walled, staghorn vascular spaces (fig. 4)

Cytology description
  • Cellular, single and tightly packed clusters of oval to spindled cells aggregated around branched capillaries
  • Usually basement membrane material
  • Nuclei are uniform and oval with finely granular chromatin and inconspicuous nucleoli
  • No mitotic figures, no necrosis (Cancer 1999;87:190)
Cytology images

Images hosted on other servers:

Irregular fragments of tissue (fig. 1)

Uniform oval or spindled cells (fig. 2)

Metachromatic basement membrane material (fig. 3)