Kidney tumor - adult malignancies

Home Chapter Home Jobs Conferences Fellowships Books

Kidney tumor - adult malignancies

Other neoplasms – adult or adult/child

Hemangiopericytoma

Reviewers: Sean Williamson, M.D. (see Reviewers page)
Revised: 30 June 2012, last major update June 2012
Copyright: (c) 2003-2012, PathologyOutlines.com, Inc.

General
=========================================================================

● Rare; <50 cases reported
● May arise in perirenal tissues or renal capsule with secondary invasion of kidney

Epidemiology
=========================================================================

● Often older patients; may be associated with hypoglycemia

Case reports
=========================================================================

● 15 year old boy with tumor of renal pelvis (Urology 2007;70:811e13)
● 43 year old woman (Urology 2008;71:755)
● 50 year old man (Internet Journal of Urology 2008;5(2))
● Bilateral metastases to kidney from CNS primary (Int Braz J Urol 2006;32:306)

Gross description
=========================================================================

● Large circumscribed tumor

Gross images
=========================================================================

Well circumscribed tumor with cystic and hemorrhagic areas

Micro description
=========================================================================

● Rich network of branching vessels with staghorn configuration, lined by single layer of endothelium, surrounded by haphazard pattern of round/oval tumor cells with indistinct cell borders

Micro images
=========================================================================

H&E and silver stain

Not kidney: uniform neoplastic cells around branched, thin-walled, staghorn vascular spaces

Cytology description
=========================================================================

● Cellular, single and tightly packed clusters of oval to spindled cells aggregated around branched capillaries
● Usually basement membrane material
● Nuclei are uniform and oval with finely granular chromatin and inconspicuous nucleoli
● No mitotic figures, no necrosis (Cancer 1999;87:190)

Cytology images
=========================================================================

Not necessarily kidney:

Irregular fragments of tissue, loose cellular aggregates and single cells (Diff-Quik)

Uniform oval or spindled cells with high N/C ratio and indistinct borders plus endothelial-lined capillary vessels (Diff-Quik)

Metachromatic basement membrane material separates tumor cells from endothelial cells (Diff-Quik)

End of Kidney tumor - adult malignancies > Adult renal cell carcinoma > Hemangiopericytoma

This information is intended for physicians and related personnel, who understand that medical information is often imperfect, and must be interpreted in the context of a patient's clinical data using reasonable medical judgment. This website should not be used as a substitute for the advice of a licensed physician.

All information on this website is protected by copyright of PathologyOutlines.com, Inc. Information from third parties may also be protected by copyright. Please contact us at copyrightPathOut@gmail.com with any questions (click here for other contact information).