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Kidney tumor - adult malignancies

Other neoplasms adult or adult/child

Leukemia


Reviewers: Sean Williamson, M.D. (see Reviewers page)
Revised: 30 June 2012, last major update June 2012
Copyright: (c) 2003-2012, PathologyOutlines.com, Inc.

General
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● Leukemic infiltrates may cause acute renal failure (Ann Diagn Pathol 2006;10:230)

Case reports
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● Congenital AML with leukemic infiltrates (J Pediatr Hematol Oncol 2003;25:240)
● Male infant with bilateral renal and orbital involvement (Pediatr Hematol Oncol 2007;24:141)
● 21 year old boy with granulocytic sarcoma presenting as isolated renal mass with subsequent development of mixed-phenotype blast crisis (Indian J Pathol Microbiol 2011;54:606)
● 42 year old man with ALL and renal failure (Nat Clin Pract Nephrol 2007;3:106)
● 72 year old man with renal infiltration by CMML (Arch Pathol Lab Med 2001;125:657)
● Megakaryoblastic leukemia with infiltration of kidney and other organs (Pathology 2011;43:517)

Gross images
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Granulocytic sarcoma in kidney

Leukemic infiltrates of ALL (arrow)

Micro images
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Chronic myelomonocytic leukemia


Granulocytic sarcoma presenting as kidney mass

Positive stains
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● PAX2 weak positivity may be seen in lymphoblastic lymphoma, possibly due to cross reaction/sequence homology with PAX5 (Am J Surg Pathol 2011;35:1186)

End of Kidney tumor - adult malignancies > Adult renal cell carcinoma > Leukemia


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