Kidney tumor - adult malignancies

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Kidney tumor - adult malignancies

Other neoplasms – adult or adult/child

Sarcoma of kidney

Reviewers: Sean Williamson, M.D. (see Reviewers page)
Revised: 5 July 2012, last major update July 2012
Copyright: (c) 2003-2012, PathologyOutlines.com, Inc.

General
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● See also anaplastic sarcoma, angiosarcoma, clear cell sarcoma (childhood), clear cell sarcoma of soft parts, Ewing's sarcoma/PNET, leiomyosarcoma, sarcomatoid renal cell carcinoma, synovial sarcoma
● Sarcomatoid carcinomas or extension of retroperitoneal sarcomas are much more common than primary renal sarcoma, and should be ruled out by search for an epithelial component and correlation with clinical history

Case reports
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● Liposarcoma (Am J Surg Pathol 1990;14:268)
● Malignant fibrous histiocytoma (71 year old man, Arch Pathol Lab Med 2000;124:913)
● Osteosarcoma (Arch Pathol Lab Med 1991;115:1262)

Gross/imaging description
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● Clear cell sarcoma commonly arises from medullar (Acta Radiol 2011;52:448)
● Leiomyosarcoma commonly arises from capsule with “buckling” of cortex
● Osteosarcoma may have dense ossification, though many are indistinguishable from RCC by imaging (Radiographics 2010;30:1525)
● Solitary fibrous tumor commonly arises from renal sinus

Micro images
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Malignant fibrous histiocytoma:

Pleomorphic-storiform pattern of malignant spindle cells

Many multinucleated giant cells

Figure 1: CT scan shows large solid mass with central, non-enhancing area; fig 2: large, well circumscribed, yellow, fleshy tumor with hemorrhage and necrosis; fig 3: short fascicles in cartwheel pattern of plump spindle cells; fig 4: hemangiopericytoma-like vessels

Osteosarcoma:

Abundant osteoid is produced

End of Kidney tumor - adult malignancies > Adult renal cell carcinoma > Sarcoma of kidney

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