Kidney nontumor
Developmental and cystic diseases
Mesothelial cysts




Topic Completed: 1 December 2011

Revised: 27 December 2018

Copyright: (c) 2003-2018, PathologyOutlines.com, Inc.

PubMed Search: Mesothelial cysts kidney
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Cite this page: Ziadie MS. Mesothelial cysts. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/kidneytumormesothelialcyst.html. Accessed February 17th, 2019.
Definition / general
  • Rare; cysts lined by mesothelial cells in vicinity of kidney that may present as renal masses
  • Also called primary retroperitoneal cysts of mesothelial origin
Radiology images

Images hosted on other servers:

Figure 1A: MRI shows cystic mass (arrows) involving upper pole;
fig 1B: cystic mass (arrows) at lower pole

Gross description
  • Thin walled, unilocular cyst filled with clear fluid
  • May be hemorrhagic
Gross images

Images hosted on other servers:

Fig A / B: hemorrhagic unilocular cysts

Microscopic (histologic) description
  • Thin walled cyst lined by single cell lining of nonpleomorphic cells with abundant eosinophilic cytoplasm, vesicular nuclei and small nucleoli
  • May have small gland-like spaces
Microscopic (histologic) images

Images hosted on other servers:

Cyst lining cells have
abundant eosinophilic
cytoplasm, vesicular
nuclei and small nucleoli

Cyst lining cells are
CEA–, keratin+,
HBME1+ and WT1+

Negative stains
Differential diagnosis
  • Lymphangioma: multicystic, has smooth muscle and lymphocytes in cyst wall and lumen, keratin+
  • Mucinous cystadenoma: ovarian-like stroma, mucin+, CEA+, negative for hyaluronic acid
  • Simple hemorrhagic cyst
Additional references