Table of ContentsDefinition / general
Cite this page: Tretiakova, M. Oncocytoid renal cell carcinoma after neuroblastoma. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/kidneytumoroncocytoidRCC.html. Accessed September 25th, 2018.
Definition / general
- Renal neoplasms occurring in patients with a history of neuroblastoma (NB) do not represent a single entity but a heterogenous group of renal cell carcinomas (RCCs) (Am J Surg Pathol 2016;40:989)
- This RCC subtype is no longer listed as an independent WHO entity due to lack of distinctive immunohistochemical and molecular markers, however it remains a provisional RCC entity in the 2016 WHO classification
- Originally described in 1999 (Am J Surg Pathol 1999;23:772), see also Urology 2007;70:178.e13
- Patients with NB have a well documented increased risk of RCC compared with the general population but tumors that arise in these patients demonstrate diverse morphologic features, including: