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Kidney tumor - cysts, children, adult benign

Benign (usually) adult tumors

Perineurioma


Reviewers: Mandolin Ziadie, M.D. (see Reviewers page)
Revised: 1 March 2012, last major update February 2012
Copyright: (c) 2003-2012, PathologyOutlines.com, Inc.

General
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● Rare and benign tumor of perineurial cells

Case reports
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● 7 year old girl (Gen Diagn Pathol 1997;143:75)
● 26 year old man (Ann Pathol 2002;22:476)
● 66 year old woman (Arch Pathol Lab Med 1993;117:654)

Micro description
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● Storiform proliferation of delicate spindle cells with elongated processes
● No long fascicles, no ectatic vessels

Micro images
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Perineurioma: site unspecified

Positive stains
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● EMA, type 4 collagen, GLUT1 and claudin1

Negative stains
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● S100

Differential diagnosis
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Low grade fibromyxoid sarcoma: focal to diffuse whirling, heavily collagenized stroma with abrupt transition to myxoid areas, often epithelioid areas, large collagen rosettes and infiltration of adjacent tissue
Schwannoma: long fascicles, ectatic blood vessels, S100+, EMA- and type 4 collagen-

End of Kidney tumor - cysts, children, adult benign > Benign (usually) adult tumors > Perineurioma

Ref Updated: 2/17/12


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