Kidney tumor
Childhood neoplasms
Renal cell carcinoma in children

Author: Mandolin Ziadie, M.D.

Revised: 19 April 2018, last major update January 2012

Copyright: (c) 2003-2018,, Inc.

PubMed Search: Renal cell carcinoma [title] children

Cite this page: Ziadie, M.S. Renal cell carcinoma in children. website. Accessed June 19th, 2018.
Case reports
Microscopic (histologic) description
  • Pediatric papillary RCC shares histologic, immunohistochemical and molecular features with adult papillary RCC
  • Xp11.2 translocation RCC shows cells with abundant clear or granular eosinophilic cytoplasm arranged in papilla or nests
  • t(6;11) RCC is composed of epithelioid cells with abundant cytoplasm, well - defined borders and small round nuclei arranged in nests / tubules
Positive stains
  • Xp11.2 translocation RCC: TFE3 (nuclear)
  • t(6;11) RCC: TFEB (nuclear)
Negative stains
Additional references