Kidney tumor
Benign (usually) adult tumors

Author: Mandolin Ziadie, M.D. (see Authors page)

Revised: 16 July 2018, last major update March 2012

Copyright: (c) 2003-2018,, Inc.

PubMed Search: Schwannoma [title] kidney

Cite this page: Ziadie, M. S. Schwannoma. website. Accessed November 15th, 2018.
Definition / general
  • Rare, benign tumor of Schwann cells
  • Also called a neurilemoma
  • < 25 cases reported in kidney through 2008
  • Mean age 47 years, range 18 - 84 years
Clinical features
Case reports
Gross description
  • Renal pelvic or parenchymal tumor that is well demarcated, yellowish tan, smooth and bulging
  • Average size, 10 cm; range 4 to 16 cm
Gross images

Images hosted on other servers:

Yellow tan lobulated intrarenal mass

Microscopic (histologic) description
  • Well circumscribed, primarily cellular subtype (predominantly Antoni A pattern) with myxoid and hypocellular areas (Antoni B)
  • May have microcystic degenerative changes with nuclear atypia (ancient schwannoma features, Can J Urol 2009;16:4948), aggregates of foamy macrophages
Microscopic (histologic) images

Images hosted on other servers:

Near total Antoni A growth pattern

Excellent circumscription

Hyalinized, ectatic blood vessel

Aggregates of foamy macrophages

Various images and stains; strongly S100+

Positive stains
Differential diagnosis