Kidney tumor
Benign adult tumors
Schwannoma


Topic Completed: 1 March 2012

Revised: 27 September 2019

Copyright: 2003-2019, PathologyOutlines.com, Inc.

PubMed Search: Schwannoma [title] kidney

Mandolin S. Ziadie, M.D.
Page views in 2019: 296
Page views in 2020 to date: 67
Cite this page: Ziadie MS. Schwannoma. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/kidneytumorschwannoma.html. Accessed April 1st, 2020.
Definition / general
  • Rare, benign tumor of Schwann cells
  • Also called a neurilemoma
Epidemiology
  • < 25 cases reported in kidney through 2008
  • Mean age 47 years, range 18 - 84 years
Clinical features
Case reports
Treatment
Gross description
  • Renal pelvic or parenchymal tumor that is well demarcated, yellowish tan, smooth and bulging
  • Average size, 10 cm; range 4 to 16 cm
Gross images

Images hosted on other servers:

Yellow tan lobulated intrarenal mass

Microscopic (histologic) description
  • Well circumscribed, primarily cellular subtype (predominantly Antoni A pattern) with myxoid and hypocellular areas (Antoni B)
  • May have microcystic degenerative changes with nuclear atypia (ancient schwannoma features, Can J Urol 2009;16:4948), aggregates of foamy macrophages
Microscopic (histologic) images

Images hosted on other servers:

Near total Antoni A growth pattern

Excellent circumscription

Hyalinized, ectatic blood vessel

Aggregates of foamy macrophages

Various images and stains; strongly S100+

Positive stains
Differential diagnosis
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