Kidney tumor
Benign (usually) adult tumors
Spiradenocylindroma


Topic Completed: 1 June 2016

Revised: 4 March 2019

Copyright: 2003-2019, PathologyOutlines.com, Inc.

PubMed search: Spiradenocylindroma

Pallav Gupta, M.D.
Mandolin S. Ziadie, M.D.
Page views in 2018: 329
Page views in 2019 to date: 206
Cite this page: Gupta P, Ziadie MS. Spiradenocylindroma. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/kidneytumorspiradeno.html. Accessed July 20th, 2019.
Epidemiology
  • Rare (one case report)
Case reports
Gross description
  • Arose in wall of renal cyst
Microscopic (histologic) description
  • Large nodules exhibiting solid or trabecular architecture, conspicuous perivascular spaces or cylindromatous small tumor cell islands in jigsaw pattern
  • Focal tubular structures and tumor cell rosettes with central PAS+ material
  • Focal epidermoid differentiation
Positive stains
Molecular / cytogenetics description
  • Isochromosome i(16p)
  • Loss of heterozygosity at 16q12-13 of the CYLD1 gene (involved in oncogenesis of familial cylindromatosis and some sporadic spiradenocylindromas)
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