Kidney tumor - cysts, children, adult benign
Benign (usually) adult tumors
Spiradenocylindroma

Authors: Pallav Gupta M.D., MAMS, PDCC, Mandolin Ziadie, M.D. (see Authors page)

Revised: 6 June 2016, last major update June 2016

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PubMed search: Spiradenocylindroma
Cite this page: Spiradenocylindroma. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/kidneytumorspiradeno.html. Accessed December 11th, 2016.
Epidemiology
  • Rare (one case report)
Case Reports
Gross Description
  • Arose in wall of renal cyst
Micro Description
  • Large nodules exhibiting solid or trabecular architecture, conspicuous perivascular spaces or cylindromatous small tumor cell islands in jigsaw pattern
  • Focal tubular structures and tumor cell rosettes with central PAS+ material
  • Focal epidermoid differentiation
Positive Stains
Molecular / Cytogenetics Description
  • Isochromosome i(16p)
  • Loss of heterozygosity at 16q12-13 of the CYLD1 gene (involved in oncogenesis of familial cylindromatosis and some sporadic spiradenocylindromas)