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Kidney tumor - cysts, children, adult benign

Benign (usually) adult tumors

Spiradenocylindroma


Reviewers: Mandolin Ziadie, M.D. (see Reviewers page)
Revised: 29 March 2012, last major update March 2012
Copyright: (c) 2003-2012, PathologyOutlines.com, Inc.

Epidemiology
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● Rare (one case report)

Case reports
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● 58 year old man (Am J Surg Pathol 2002;26:119)

Gross description
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● Arose in wall of renal cyst

Micro description
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● Large nodules exhibiting solid or trabecular architecture, conspicuous perivascular spaces or cylindromatous small tumor cell islands in jigsaw pattern
● Focal tubular structures and tumor cell rosettes with central PAS+ material
● Focal epidermoid differentiation

Positive stains
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● CK 5/6, 34betaE12, AE1/3 and E-cadherin

Molecular description
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● i(16p) affecting CYLD1 gene (involved in oncogenesis of familial cylindromatosis and some sporadic spiradenocylindromas)

End of Kidney tumor - cysts, children, adult benign > Benign (usually) adult tumors > Spiradenocylindroma


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