Larynx and hypopharynx
Benign tumors
Mucous membrane plasmacytosis

Author: Nat Pernick, M.D. (see Authors page)

Revised: 20 March 2018, last major update November 2013

Copyright: (c) 2002-2018, PathologyOutlines.com, Inc.

PubMed Search: Mucous membrane plasmacytosis larynx

Cite this page: Pernick, N. Mucous membrane plasmacytosis. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/larynxmucousmembraneplasmacytosis.html. Accessed August 19th, 2018.
Definition / general
  • For upper aerodigestive tract cases, 2/3 were men, mean age 54 years, range 40 - 67 years
  • Affects larynx, pharynx, palate, lips, mouth, tongue and trachea
Treatment
  • None successful although apparently a benign process
Gross description
  • Cobblestone or warty appearance of mucosa
Microscopic (histologic) description
  • Psoriasiform epithelial hyperplasia with dyskeratosis and dense subepithelial plasmacytosis
  • Plasma cells are mature but diffuse and expansive
Stains
  • Polyclonal light chains
Additional references