Larynx and hypopharynx
Squamous cell carcinoma
Pyriform sinus squamous cell carcinoma

Author: Nat Pernick, M.D. (see Authors page)

Revised: 23 March 2018, last major update November 2013

Copyright: (c) 2002-2018,, Inc.

PubMed Search: Pyriform sinus [title] squamous cell carcinoma [title]

Table of Contents
Definition / general | Treatment
Cite this page: Pernick, N. Pyriform sinus squamous cell carcinoma. website. Accessed July 22nd, 2018.
Definition / general
  • Close to, although not part of larynx; these tumors frequently invade the supraglottic larynx under an intact mucous membrane
  • Usually destroys posterior edge of thyroid cartilage
  • Usually associated with alcoholism
  • 2/3 die of disease or associated medical disorders
  • Total laryngectomy with preoperative chemotherapy or postoperative radiation therapy