Leukemia - Acute
B lymphoblastic leukemia / lymphoma with t(5;14)(q31;q32); IL3-IGH

Author: Daniela Mihova, M.D. (see Authors page)

Revised: 12 April 2018, last major update February 2013

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PubMed Search: B lymphoblastic leukemia IL3-IGH

Cite this page: Mihova, D. B lymphoblastic leukemia / lymphoma with t(5;14)(q31;q32); IL3-IGH. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/leukemiat514.html. Accessed August 16th, 2018.
Definition / general
  • Diagnosis based on immunophenotype and genetic findings, even with low blast count
  • Very rare; < 1% of all ALL; both children and adults (Blood 1989;73:2081)
  • Presents with variable eosinophilia; may be asymptomatic and lack any blasts (Medicine (Baltimore) 1990;69:232)
Case reports
Microscopic (histologic) description
  • CD19+ CD10+ lymphoblasts with circulating reactive eosinophils