Leukemia - Acute
PreB ALL
B lymphoblastic leukemia / lymphoma with t(5;14)(q31;q32); IL3-IGH




Topic Completed: 1 February 2013

Revised: 22 January 2019, last major update February 2013

Copyright: (c) 2001-2018, PathologyOutlines.com, Inc.

PubMed Search: B lymphoblastic leukemia IL3-IGH

Page views in 2018: 87
Page views in 2019 to date: 28
Cite this page: Mihova D. B lymphoblastic leukemia / lymphoma with t(5;14)(q31;q32); IL3-IGH. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/leukemiat514.html. Accessed February 21st, 2019.
Definition / general
  • Diagnosis based on immunophenotype and genetic findings, even with low blast count
  • Very rare; < 1% of all ALL; both children and adults (Blood 1989;73:2081)
  • Presents with variable eosinophilia; may be asymptomatic and lack any blasts (Medicine (Baltimore) 1990;69:232)
Case reports
Microscopic (histologic) description
  • CD19+ CD10+ lymphoblasts with circulating reactive eosinophils