Liver and intrahepatic bile ducts - nontumor
Systemic diseases / conditions
Congestive heart failure



Topic Completed: 1 May 2012

Revised: 23 January 2019, last major update May 2012

Copyright: (c) 2002-2017, PathologyOutlines.com, Inc.

PubMed Search: Congestive heart failure[TI] liver[TI]


Komal Arora, M.D.
Page views in 2018: 1,409
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Cite this page: Arora K. Congestive heart failure. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/liverCHF.html. Accessed October 17th, 2019.
Definition / general
  • Also called cardiac sclerosis
  • Mild elevation of serum ALT and AST, mild jaundice
  • Rarely progresses to fully developed cirrhosis
Microscopic (histologic) description
  • Centrilobular congestion and necrosis, central stellate fibrosis
  • Sinusoidal dilation which can compress liver cell plates, hemosiderin and lipochrome laden macrophages
  • May have cholestasis at edge of fibrotic zone, PAS+ globules in ischemic central zones
  • Portal tracts spared until late
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