Liver and intrahepatic bile ducts-nontumor

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Liver and intrahepatic bile ducts-nontumor

Systemic disease/conditions

Congestive heart failure

Reviewers: Komal Arora, M.D. (see Reviewers page)
Revised: 16 May 2012, last major update May 2012
Copyright: (c) 2004-2012, PathologyOutlines.com, Inc.

General
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● Also called cardiac sclerosis
● Mild elevation of serum ALT and AST, mild jaundice
● Rarely progresses to fully developed cirrhosis

Micro description
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● Centrilobular congestion and necrosis, central stellate fibrosis
● Sinusoidal dilation which can compress liver cell plates, hemosiderin and lipochrome laden macrophages
● May have cholestasis at edge of fibrotic zone, PAS+ globules in ischemic central zones
● Portal tracts spared until late

End of Liver and intrahepatic bile ducts-nontumor > Systemic disease/conditions > Congestive heart failure

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