Liver and intrahepatic bile ducts - nontumor
Systemic diseases / conditions
Congestive heart failure

Author: Komal Arora, M.D. (see Authors page)

Revised: 10 November 2017, last major update May 2012

Copyright: (c) 2002-2017,, Inc.

PubMed Search: Congestive heart failure[TI] liver[TI]

Cite this page: Arora, K. Congestive heart failure. website. Accessed July 23rd, 2018.
Definition / general
  • Also called cardiac sclerosis
  • Mild elevation of serum ALT and AST, mild jaundice
  • Rarely progresses to fully developed cirrhosis
Microscopic (histologic) description
  • Centrilobular congestion and necrosis, central stellate fibrosis
  • Sinusoidal dilation which can compress liver cell plates, hemosiderin and lipochrome laden macrophages
  • May have cholestasis at edge of fibrotic zone, PAS+ globules in ischemic central zones
  • Portal tracts spared until late