Liver and intrahepatic bile ducts - nontumor
Metabolic diseases
Heme oxygenase-1 deficiency

Topic Completed: 1 April 2012

Revised: 23 January 2019, last major update April 2012

Copyright: (c) 2002-2017,, Inc.

PubMed Search: Heme oxygenase-1 deficiency

Komal Arora, M.D.
Page views in 2019: 56
Page views in 2020 to date: 9
Cite this page: Arora K. Heme oxygenase-1 deficiency. website. Accessed February 18th, 2020.
Definition / general
  • Enzyme degrades heme into biliverdin, carbon monoxide and free iron; also is antioxidant and has role in iron balance (J Cell Mol Med 2009;13:3091)
Case reports
Microscopic (histologic) description
  • Amyloid present in liver and adrenal glands, mesangioproliferative glomerular changes in kidney, fatty streaks and fibrous plaques in aorta
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