Liver and intrahepatic bile ducts - nontumor
Metabolic diseases
Heme oxygenase-1 deficiency

Author: Komal Arora, M.D. (see Authors page)

Revised: 27 October 2017, last major update April 2012

Copyright: (c) 2002-2017,, Inc.

PubMed Search: Heme oxygenase-1 deficiency

Cite this page: Arora, K. Heme oxygenase-1 deficiency. website. Accessed April 21st, 2018.
Definition / general
  • Enzyme degrades heme into biliverdin, carbon monoxide and free iron; also is antioxidant and has role in iron balance (J Cell Mol Med 2009;13:3091)
Case reports
Microscopic (histologic) description
  • Amyloid present in liver and adrenal glands, mesangioproliferative glomerular changes in kidney, fatty streaks and fibrous plaques in aorta