Liver and intrahepatic bile ducts - nontumor
Transplantation
Acute graft rejection

Author: Komal Arora, M.D.

Revised: 20 June 2018, last major update May 2012

Copyright: (c) 2002-2018, PathologyOutlines.com, Inc.

PubMed Search: Acute rejection[TI] liver[TI] free full text[sb]

Cite this page: Arora, K. Acute graft rejection. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/liveracutegraftrejection.html. Accessed July 23rd, 2018.
Definition / general
Treatment
  • Cautious increase in immunosuppression (even if posttransplant lymphoproliferative disorder)
Microscopic (histologic) description
  • Portal infiltrate of lymphocytes and variable eosinophils and neutrophils that damage bile ducts and venous endothelium
  • No / minimal hepatocyte damage
  • Also loss of bile ducts, arteritis, central ischemic damage with ballooning degeneration and hepatocyte dropout
Microscopic (histologic) images

Images hosted on other servers:

Moderate acute rejection with bile duct damage

Severe acute rejection

Loss of bile ducts