Liver and intrahepatic bile ducts - nontumor
Transplantation
Acute graft rejection




Topic Completed: 1 May 2012

Revised: 23 January 2019, last major update May 2012

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PubMed Search: Acute rejection[TI] liver[TI] free full text[sb]

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Cite this page: Arora K. Acute graft rejection. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/liveracutegraftrejection.html. Accessed May 23rd, 2019.
Definition / general
Treatment
  • Cautious increase in immunosuppression (even if posttransplant lymphoproliferative disorder)
Microscopic (histologic) description
  • Portal infiltrate of lymphocytes and variable eosinophils and neutrophils that damage bile ducts and venous endothelium
  • No / minimal hepatocyte damage
  • Also loss of bile ducts, arteritis, central ischemic damage with ballooning degeneration and hepatocyte dropout
Microscopic (histologic) images

Images hosted on other servers:

Moderate acute rejection with bile duct damage

Severe acute rejection

Loss of bile ducts

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