Liver and intrahepatic bile ducts-nontumor
Biliary tract disease
Chronic large duct obstruction
Reviewers: Komal Arora, M.D. (see Reviewers page)
Revised: 12 May 2012, last major update May 2012
Copyright: (c) 2004-2012, PathologyOutlines.com, Inc.
● Impacted stones, recurrent passed stones, biliary fibrosis, primary sclerosing cholangitis
● Diffuse bile ductular proliferation with more fibrosis than acute cases
● Also primarily chronic inflammatory infiltrate, onion skin cuffing of fibroblasts around large bile ducts, variable cholestasis, variable Mallory’s hyaline in periportal hepatocytes
● Usually no edema, minimal neutrophils, minimal interlobular bile ducts
● Hepatitis C, primary sclerosing cholangitis, primary biliary cirrhosis
End of Liver and intrahepatic bile ducts-nontumor > Biliary tract disease > Chronic large duct obstruction
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