Liver and intrahepatic bile ducts nontumor
General concepts
Alcoholic cirrhosis

Topic Completed: 1 April 2012

Revised: 9 March 2020

Copyright: 2003-2020,, Inc.

PubMed Search: Alcoholic cirrhosis [title]

Related topics: Cirrhosis

Komal Arora, M.D.
Page views in 2019: 833
Page views in 2020 to date: 360
Cite this page: Arora, K. Alcoholic cirrhosis. website. Accessed April 9th, 2020.
Definition / general
  • Larger nodules are associated with periodic alcohol abstinence, causing more regeneration of hepatocyte
Microscopic (histologic) description
  • Micronodular cirrhosis, Mallory bodies, fatty change
  • Also perivenular and pericellular fibrosis (highlighted with trichrome stain) with partial / complete obliteration of central vein (identify as central vein due to lack of arterioles)
  • More prominent bridging from central zone to central zone and central zone to portal zone than in other causes of cirrhosis
  • Usually few inflammatory cells unless superimposed viral or alcoholic hepatitis
Microscopic (histologic) images
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Alcoholic cirrhosis

Differential diagnosis
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