Liver and intrahepatic bile ducts-nontumor

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Liver and intrahepatic bile ducts-nontumor

Developmental anomalies/cysts

Down's syndrome

Reviewers: Komal Arora, M.D. (see Reviewers page)
Revised: 23 April 2012, last major update April 2012
Copyright: (c) 2004-2012, PathologyOutlines.com, Inc.

General
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● Increased liver volume at gestational weeks 11 and 13 (Prenat Diagn 2011;31:28)
● Hepatic dysfunction in infant with Trisomy 21 is likely due to transient myeloproliferative disorder with hepatic infiltration by hematopoietic elements, associated with secondary hemosiderosis
● Case report associated with liver fibrosis, thought due to megakaryocyte derived transforming growth factor beta (Hum Pathol 1999;30:474)

Micro images
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Liver failure with porto-pulmonary hypertension secondary to neonatal hemochromatosis

End of Liver and intrahepatic bile ducts-nontumor > Developmental anomalies/cysts > Down's syndrome

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