Liver and intrahepatic bile ducts-nontumor

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Liver and intrahepatic bile ducts-nontumor

Infectious (non-viral) disorders

Visceral leishmaniasis

Reviewers: Komal Arora, M.D. (see Reviewers page)
Revised: 12 May 2012, last major update May 2012
Copyright: (c) 2004-2012, PathologyOutlines.com, Inc.

General
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● Cases due to Leishmania infantum are endemic in Southern France, associated with HIV (Hum Pathol 2000;31:75)
● Fever, hepatosplenomegaly, pancytopenia are common; often fatal when associated with HIV
● Diagnosis: amastigotes (Leishmania donovani [L-D] bodies) in bone marrow smears or biopsies (skin, GI, liver, duodenum)

Micro description
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● Rounded bodies 2-3 microns within macrophages and sinusoidal endothelial cells

Micro images
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Small rounded bodies within macrophages

End of Liver and intrahepatic bile ducts-nontumor > Infectious (non-viral) disorders > Visceral leishmaniasis

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