Liver and intrahepatic bile ducts-nontumor

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Liver and intrahepatic bile ducts-nontumor

Infectious (non-viral) disorders

Microsporidia

Reviewers: Komal Arora, M.D. (see Reviewers page)
Revised: 12 May 2012, last major update May 2012
Copyright: (c) 2004-2012, PathologyOutlines.com, Inc.

Case reports
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● 33 year old Italian woman with AIDS (Mod Pathol 2002;15:577)

Micro description
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● Large necrotic lesions with rings of macrophages, fibrosis and occasional lymphocytes and granulocytes
● 2 micron oval, pink, slightly refractile bodies present in necrotic areas and surrounding cells
● Focally associated with granulomatous reactions, occasionally found in hepatic sinusoidal cells

Micro images
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Fibrosis surrounding necrotic areas

Red stained spores within macrophage-like cells

Indirect immunofluorescence

Positive stains
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● Kinyoun acid-fast, Giemsa, modified Trichrome

Electron microscopy images (adrenal gland)
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Spore containing polar tube arranged in single row with six coils

End of Liver and intrahepatic bile ducts-nontumor > Infectious (non-viral) disorders > Microsporidia

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