Liver and intrahepatic bile ducts - nontumor
Biliary tract disease
Oriental cholangiohepatitis

Author: Komal Arora, M.D. (see Authors page)

Revised: 7 November 2017, last major update May 2012

Copyright: (c) 2002-2017,, Inc.

PubMed Search: Oriental cholangiohepatitis[TIAB]

Cite this page: Arora, K. Oriental cholangiohepatitis. website. Accessed July 23rd, 2018.
Definition / general
  • Also called recurrent pyogenic cholangitis
  • Endemic in Southeast Asia, usually young adults
  • Symptoms: recurrent attacks of sepsis, usually E. coli, with associated abdominal pain, fever and jaundice
Radiology description
  • Dilation of extrahepatic bile ducts with relatively mild / no dilation of intrahepatic ducts, localized dilatation of the lobar or segmental bile ducts, increased periportal echogenicity, segmental hepatic atrophy, gallstones
  • Localized intrahepatic segmental ductal stenosis may be present, especially in the lateral segment of the left lobe or posterior segment of the right hepatic lobe
Microscopic (histologic) description
  • Proliferation of bile ducts and inflammatory cells along the periportal spaces and hepatic parenchyma
  • Hepatic and intraductal abscesses