Liver and intrahepatic bile ducts-nontumor - Oriental cholangiohepatitis

Home Chapter Home Jobs Conferences Fellowships Books

Liver and intrahepatic bile ducts-nontumor

Biliary tract disease

Oriental cholangiohepatitis

Reviewers: Komal Arora, M.D. (see Reviewers page)
Revised: 14 May 2012, last major update May 2012
Copyright: (c) 2004-2012, PathologyOutlines.com, Inc.

General
=========================================================================

● Also called recurrent pyogenic cholangitis
● Endemic in Southeast Asia, usually young adults
● Symptoms: recurrent attacks of sepsis, usually E. coli, with associated abdominal pain, fever, and jaundice

Xray
=========================================================================

● Dilation of extrahepatic bile ducts with relatively mild/no dilation of intrahepatic ducts, localized dilatation of the lobar or segmental bile ducts, increased periportal echogenicity, segmental hepatic atrophy, gallstones
● Localized intrahepatic segmental ductal stenosis may be present, especially in the lateral segment of the left lobe or posterior segment of the right hepatic lobe

Micro description
=========================================================================

● Proliferation of bile ducts and inflammatory cells along the periportal spaces and hepatic parenchyma
● Hepatic and intraductal abscesses

Micro images
=========================================================================

Microphotograph of resected liver specimen shows soft, pigmented stone (long arrow) in dilated medium-sized bile duct. Note also severe thickening of small bile ducts and periductal fibrosis (short arrows) obliterating lumen of bile ducts and encroaching on hepatic parenchyma. (Masson’s trichrome stain, original magnification x8)

Additional references
=========================================================================

● Adv Anat Pathol 2011;18:318, AJR Am J Roentgenol.1991;157:1

End of Liver and intrahepatic bile ducts-nontumor > Biliary tract disease > Oriental cholangiohepatitis

This information is intended for physicians and related personnel, who understand that medical information is often imperfect, and must be interpreted in the context of a patient's clinical data using reasonable medical judgment. This website should not be used as a substitute for the advice of a licensed physician.

All information on this website is protected by copyright of PathologyOutlines.com, Inc. Information from third parties may also be protected by copyright. Please contact us at copyrightPathOut@gmail.com with any questions (click here for other contact information).