Liver and intrahepatic bile ducts - nontumor
Biliary tract disease
Oriental cholangiohepatitis

Topic Completed: 1 May 2012

Revised: 25 April 2019

Revised: 23 January 2019, last major update May 2012

Copyright: (c) 2002-2017,, Inc.

PubMed Search: Oriental cholangiohepatitis[TIAB]

Komal Arora, M.D.
Page views in 2018: 301
Page views in 2019 to date: 211
Cite this page: Arora K. Oriental cholangiohepatitis. website. Accessed September 18th, 2019.
Definition / general
  • Also called recurrent pyogenic cholangitis
  • Endemic in Southeast Asia, usually young adults
  • Symptoms: recurrent attacks of sepsis, usually E. coli, with associated abdominal pain, fever and jaundice
Radiology description
  • Dilation of extrahepatic bile ducts with relatively mild / no dilation of intrahepatic ducts, localized dilatation of the lobar or segmental bile ducts, increased periportal echogenicity, segmental hepatic atrophy, gallstones
  • Localized intrahepatic segmental ductal stenosis may be present, especially in the lateral segment of the left lobe or posterior segment of the right hepatic lobe
Microscopic (histologic) description
  • Proliferation of bile ducts and inflammatory cells along the periportal spaces and hepatic parenchyma
  • Hepatic and intraductal abscesses
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