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Liver and intrahepatic bile ducts-nontumor

Infectious (non-viral) disorders

Orientia tsutsugamushi


Reviewers: Komal Arora, M.D. (see Reviewers page)
Revised: 12 May 2012, last major update May 2012
Copyright: (c) 2004-2012, PathologyOutlines.com, Inc.

General
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● Formerly called Rickettsia tsutsugamushi
● Rickettsiael agent of scrub typhus, a chigger-borne zoonosis highly prevalent and life-threatening in tropical Asia and islands of western Pacific Ocean
● Present within liver and spleen macrophages and cardiac muscle cells
● Also endothelial cells of heart, lung, brain, kidney, pancreas, skin
● Transmitted to humans via larval mite (chigger) during feeding

Micro images
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Immunostained organisms in hepatic and splenic macrophages

Electron macroscopy images
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Organism in cardiac myocytes

Additional references
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Mod Pathol 2001;14:752

End of Liver and intrahepatic bile ducts-nontumor > Infectious (non-viral) disorders > Orientia tsutsugamushi


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