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Liver and intrahepatic bile ducts - nontumor
Transplantation
Pseudopeliotic steatosis




Topic Completed: 1 May 2012

Revised: 23 January 2019, last major update May 2012

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PubMed Search: Lipopeliosis

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Table of Contents
Definition / general | Pathophysiology | Microscopic (histologic) description | Additional references
Cite this page: Arora K. Pseudopeliotic steatosis. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/liverpseudopeliotic.html. Accessed February 18th, 2019.
Definition / general
  • Formerly called lipopeliosis
  • Preservation injury causes their death with loss of fat
  • Fat droplets accumulate to form fat globules that mimic dilated sinusoids (week 1), then are surrounded by macrophages and cleared by 3 - 4 weeks
Pathophysiology
  • Steatotic hepatocytes are present in donor liver
Microscopic (histologic) description
  • Apparent sinusoidal engorgement by large fat globules, although fat globules are actually outside sinusoids when collagen IV immunostaining is performed
  • Variably damaged hepatocytes
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