Liver and intrahepatic bile ducts - nontumor
Pseudopeliotic steatosis

Author: Komal Arora, M.D. (see Authors page)

Revised: 14 November 2017, last major update May 2012

Copyright: (c) 2002-2017,, Inc.

PubMed Search: Lipopeliosis

Cite this page: Arora, K. Pseudopeliotic steatosis. website. Accessed March 19th, 2018.
Definition / general
  • Formerly called lipopeliosis
  • Preservation injury causes their death with loss of fat
  • Fat droplets accumulate to form fat globules that mimic dilated sinusoids (week 1), then are surrounded by macrophages and cleared by 3 - 4 weeks
  • Steatotic hepatocytes are present in donor liver
Microscopic (histologic) description
  • Apparent sinusoidal engorgement by large fat globules, although fat globules are actually outside sinusoids when collagen IV immunostaining is performed
  • Variably damaged hepatocytes