Liver and intrahepatic bile ducts - tumor
Other malignancies
Kaposi sarcoma (KS)

Author: Deepali Jain, M.D. (see Authors page)

Revised: 1 December 2017, last major update February 2012

Copyright: (c) 2002-2017,, Inc.

PubMed Search: Kaposi sarcoma[TI] liver

See also: Soft tissue chapter
Page views in 2018: 198
Page views in 2019 to date: 10
Cite this page: Jain, D. Kaposi sarcoma (KS). website. Accessed January 19th, 2019.
Definition / general
  • Malignant vascular neoplasm with blunt endothelial cells, erythrocyte extravasation, hemosiderin deposition, usually in HIV+ patients; incidental finding at autopsy in 15% with AIDS (IARC: 9140 / 3 Kaposi Sarcoma [Accessed 1 December 2017])
  • Present in liver in 12 - 25% of fatal cases of KS elsewhere in body
Gross description
  • Hemorrhagic multifocal spongy nodules, 5 - 7 cm
Microscopic (histologic) description
  • Spindle cells with hyaline globules and vasoformative channels with extravasated red blood cells
  • Lesions centered on portal tracts
Positive stains
Differential diagnosis