Liver and intrahepatic bile ducts - tumor
Other malignancies
Kaposi sarcoma (KS)

Topic Completed: 1 February 2012

Revised: 28 January 2019, last major update February 2012

Copyright: (c) 2002-2017,, Inc.

PubMed Search: Kaposi sarcoma[TI] liver

See also: Soft tissue chapter

Deepali Jain, M.D.
Page views in 2019: 190
Page views in 2020 to date: 46
Cite this page: Jain D. Kaposi sarcoma (KS). website. Accessed February 27th, 2020.
Definition / general
  • Malignant vascular neoplasm with blunt endothelial cells, erythrocyte extravasation, hemosiderin deposition, usually in HIV+ patients; incidental finding at autopsy in 15% with AIDS (IARC: 9140 / 3 Kaposi Sarcoma [Accessed 1 December 2017])
  • Present in liver in 12 - 25% of fatal cases of KS elsewhere in body
Gross description
  • Hemorrhagic multifocal spongy nodules, 5 - 7 cm
Microscopic (histologic) description
  • Spindle cells with hyaline globules and vasoformative channels with extravasated red blood cells
  • Lesions centered on portal tracts
Positive stains
Differential diagnosis
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