Liver and intrahepatic bile ducts - tumor

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Liver and intrahepatic bile ducts - tumor

Other malignancies

Kaposi’s sarcoma (KS)

Reviewers: Deepali Jain, M.D. (see Reviewers page)
Revised: 9 January 2013, last major update February 2012
Copyright: (c) 2004-2013, PathologyOutlines.com, Inc.

See also Soft Tissue Tumors chapter

General
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● Malignant vascular neoplasm with blunt endothelial cells, erythrocyte extravasation, hemosiderin deposition, usually in HIV+ patients; incidental finding at autopsy in 15% with AIDS (WHO)
● Present in liver in 12-25% of fatal cases of KS elsewhere in body

Gross description
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● Hemorrhagic multifocal spongy nodules, 5-7 cm

Gross images
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Multiple dark brown lesions in large portal areas

Micro description
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● Spindle cells with hyaline globules and vasoformative channels with extravasated red blood cells
● Lesions centered on portal tracts

Micro images
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Spindle cells and slit-like vascular spaces

Positive stains
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● CD31, CD34

Differential diagnosis
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● Bacillary peliosis hepatis

End of Liver and intrahepatic bile ducts - tumor > Other malignancies > Kaposi’s sarcoma (KS)

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